Good question. There are already some good answers here, but beyond the mechanistics, you should determine whether or not entrepreneurship is right for you. Becoming an entrepreneur is a career and lifestyle choice ... and a very rewarding choice for those who fit. Some questions that you can ask yourself (and be honest):

1. How do you handle extreme uncertainty? You won't know when you'll get your next paycheck or when you'll land that first customer.

2. How are you at making big decisions? While you should get advice from mentors, partners, etc., you will be making the final decisions.

3, How responsible are you? Many things need to get done and you'll be responsible for all of them until you hire people to help.

4. How is your support system? If you have a family, then make sure they are OK with your decision. Have trusted mentors in place.

These are just a few questions to consider.

Taking the entrepreneurial path can be very rewarding and fulfilling. I decided over 20 years ago (during grad school) to be an entrepreneur and have thoroughly enjoyed it.

Good luck!